Grifola Frondosa / Maitake Mushroom
Classification:Raw Materials
Release time:2022-04-21
Grifola frondosa, also known as maitake mushrooms and chestnut mushrooms, is an edible fungus whose yield is much lower than that of shiitake mushrooms and oyster mushrooms, but its nutritional value has been affirmed over the years. Japanese cancer patients seriously injured by the atomic bomb in Nagasaki are called "Kings of Anti-Cancer".
Benefits of maitake
The active ingredient in Grifola frondosa polysaccharide can effectively promote insulin secretion and inhibit glucagon secretion, thereby significantly reducing the blood sugar level of the body and achieving the purpose of lowering the blood sugar level. At the same time, it can also effectively promote the metabolism of liver fat and blood lipids, and reduce the levels of cholesterol, triglycerides and phospholipids in hyperlipidemia serum. Blood pressure can be adjusted in both directions.
In addition, the Grifola frondosa polysaccharide compound also has the effect of inhibiting HIV activity.
Not only that, Kubo's research also showed that a variety of Grifola frondosa polysaccharides can effectively reduce the transformation of experimental hepatitis to autoimmune chronic hepatitis.
In general, maitake does have a lot of effects, and if used rationally, it has many benefits to our human body.
Anti-cancer efficacy has been recognized by many countries
Researchers such as Hiroaki Namba in Japan have conducted research on medicinal fungi such as Ganoderma lucidum, shiitake mushrooms, matsutake mushrooms, Hericium erinaceus, Cordyceps sinensis, Grifola frondosa, and found that the anticancer effect of Grifola frondosa is much higher than that of other fungi.
The reason why Grifola frondosa is considered to be able to prevent cancer and resist cancer is mainly because it contains a component called Grifola frondosa polysaccharide, which can activate the function of immune cells, such as T lymphocytes, B lymphocytes, and macrophages. and natural killer cells (NK) and other immune cells to relieve pain; if combined with chemotherapy, it can also effectively reduce the toxic side effects of chemotherapy and improve the symptoms of cancer patients; not only that, it also helps to inhibit cancer recurrence and metastasis.
Since then, research on maitake-related cancer resistance has attracted attention and has been carried out globally.
For example, Hu Xinyu et al. conducted in vitro cell experiments to prove that Grifola frondosa extract can effectively reduce the survival rate of PLC/PRF/5 and HepG2 cells, and improve the release of cellular lactate dehydrogenase. Inoculated with PLC/PRF/5 cells of liver cancer, it was proved by experiments that Grifola frondosa could inhibit the growth of cancer in PLC/PRF/5 ectopic tumor-bearing nude mice model.
Alternatively, Zhao F et al. conducted in vitro apoptosis and autophagy experiments with human liver cancer SMMC-7721 and HepG2 cells, and found that the combined application of Grifola frondosa polysaccharide and VC could induce apoptosis and autophagy of human liver cancer SMMC-7721 and HepG2 cells. , which laid a preliminary research foundation for the in vivo study of Grifola frondosa polysaccharide combination.
In general, Grifola frondosa plays a great role in resisting cancer, so it is also recognized internationally. Countries such as the United States, Japan, Canada and other countries use it as a first-line drug for clinical tumor biochemotherapy, and in order to speed up Grifola frondosa Flower-related drugs entered the clinical tumor clinic, and the US FDA even broke the convention, skipping Phase 1 clinical trials and entering Phase 2 directly, because they had great expectations for the anti-cancer efficacy of Grifola frondosa.